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2026/01/12

CRDMO: New Conjugates Are Expanding the Boundaries of Precision Medicine

As precision medicine continues to advance, the ability to efficiently and specifically deliver therapeutic agents to diseased tissues has become a critical focus in drug development. One promising strategy involves conjugating therapeutic payloads with ligands that can bind to specific proteins or receptors expressed in target tissues. This approach has demonstrated both safety and efficacy in clinical practice. In addition to monoclonal antibodies, small molecules, peptides, and oligonucleotides have also emerged as targeting ligands, enabling precise drug delivery. However, these conjugation strategies often come with significant synthetic complexity. WuXi AppTec’s deep expertise in chemistry has laid a strong foundation for the development of such next-generation therapies. Through its comprehensive WuXi TIDES platform, WuXi AppTec provides integrated solutions for complex conjugates. This article explores various conjugation strategies that enhance tissue-specific drug delivery and highlights how WuXi TIDES accelerates conjugates development through its integrated CRDMO platform.

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2026/01/05

Small-Molecule GLP-1 Receptor Agonists: Expanding the Horizon of Metabolic Disease Treatment

In recent years, glucagon-like peptide-1 receptor agonists (GLP-1RAs) have achieved continuous breakthroughs in the treatment of diabetes and obesity, reshaping the global therapeutic paradigm.

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